q2-fmt

q2-fmt assesses the extent of microbiome engraftment following fecal microbiota transplant using diverse analytical methods informed by literature review.

Key Features:

• Community Coalescence Analysis: Evaluates the integration of transplanted microbial communities with the recipient's existing microbiome.
• Indicator Features: Identifies specific microbial features that indicate successful engraftment following fecal microbiota transplant.
• Resilience Assessment: Measures the stability and recovery dynamics of the microbiome post-transplant.

Scientific Applications:

• FMT Engraftment Evaluation: Quantifies the degree to which donor microbiota establishes in recipient subjects after fecal microbiota transplant.
• Microbiome Community Dynamics: Analyzes community coalescence processes and ecological integration of transplanted microbes.
• Post-Transplant Monitoring: Tracks microbiome resilience and identifies indicator features for successful engraftment outcomes.

Methodology:

Methods were informed by a literature review on approaches for assessing FMT engraftment and are implemented as a QIIME 2 plugin.