qPTMplants

qPTMplants aggregates quantitative post-translational modification (PTM) data in plants to enable analysis of PTM occurrence and dynamics across species and experimental conditions.


Key Features:

  • Data scale: Contains 1,242,365 experimentally identified PTM events on 429,821 nonredundant sites from 123,551 proteins.
  • Quantitative coverage: Provides quantification for 620,509 events across 136,700 PTM sites on 55,361 proteins under 354 distinct conditions.
  • PTM and species diversity: Documents 23 types of PTMs across 43 plant species and 583 conditions.
  • Provenance: Assembled from 293 published studies.
  • Experimental detail curation: Manually curates experimental metadata including conditions, samples, instruments, and methods.
  • Source technology: Data are derived from mass spectrometry-based proteomic technologies.
  • Annotations: Integrates sequence and structural characteristic annotations for PTM sites.

Scientific Applications:

  • PTM profiling: Enables large-scale identification and cataloging of PTM sites and events across plant proteomes.
  • Quantitative dynamics: Supports analysis of condition-specific and dynamic regulation of PTMs under diverse experimental conditions.
  • Comparative studies: Facilitates cross-species comparison of PTM patterns among 43 plant species.
  • Proteomic research: Provides curated, mass spectrometry-derived data and annotations for downstream proteomic and structural analyses.

Methodology:

Data were compiled from 293 published, mass spectrometry-based proteomic studies, manually curated for experimental details (conditions, samples, instruments, methods), and integrated with sequence and structural characteristic annotations.

Topics

Details

Cost:
Free of charge
Tool Type:
web application
Operating Systems:
Mac, Linux, Windows
Added:
3/30/2022
Last Updated:
3/30/2022

Operations

Publications

Xue H, Zhang Q, Wang P, Cao B, Jia C, Cheng B, Shi Y, Guo W, Wang Z, Liu Z, Cheng H. qPTMplants: an integrative database of quantitative post-translational modifications in plants. Nucleic Acids Research. 2021;50(D1):D1491-D1499. doi:10.1093/nar/gkab945. PMID:34718741. PMCID:PMC8728288.

PMID: 34718741
PMCID: PMC8728288
Funding: - National Natural Science Foundation of China: 31601067, 62002329, 91953123, U2004152 - Guangdong Innovative and Entrepreneurial Research Team Program: 2017ZT07S096 - Tip-top Scientific and Technical Innovative Youth Talents of Guangdong Special Support Program: 2019TQ05Y351 - Key Scientific and Technological Projects of Henan Province: 212102310083 - China Postdoctoral Research Foundation: 2021M692915 - Henan Postdoctoral Foundation: 202002021