qPTMplants
qPTMplants aggregates quantitative post-translational modification (PTM) data in plants to enable analysis of PTM occurrence and dynamics across species and experimental conditions.
Key Features:
- Data scale: Contains 1,242,365 experimentally identified PTM events on 429,821 nonredundant sites from 123,551 proteins.
- Quantitative coverage: Provides quantification for 620,509 events across 136,700 PTM sites on 55,361 proteins under 354 distinct conditions.
- PTM and species diversity: Documents 23 types of PTMs across 43 plant species and 583 conditions.
- Provenance: Assembled from 293 published studies.
- Experimental detail curation: Manually curates experimental metadata including conditions, samples, instruments, and methods.
- Source technology: Data are derived from mass spectrometry-based proteomic technologies.
- Annotations: Integrates sequence and structural characteristic annotations for PTM sites.
Scientific Applications:
- PTM profiling: Enables large-scale identification and cataloging of PTM sites and events across plant proteomes.
- Quantitative dynamics: Supports analysis of condition-specific and dynamic regulation of PTMs under diverse experimental conditions.
- Comparative studies: Facilitates cross-species comparison of PTM patterns among 43 plant species.
- Proteomic research: Provides curated, mass spectrometry-derived data and annotations for downstream proteomic and structural analyses.
Methodology:
Data were compiled from 293 published, mass spectrometry-based proteomic studies, manually curated for experimental details (conditions, samples, instruments, methods), and integrated with sequence and structural characteristic annotations.
Topics
Details
- Cost:
- Free of charge
- Tool Type:
- web application
- Operating Systems:
- Mac, Linux, Windows
- Added:
- 3/30/2022
- Last Updated:
- 3/30/2022
Operations
Publications
Xue H, Zhang Q, Wang P, Cao B, Jia C, Cheng B, Shi Y, Guo W, Wang Z, Liu Z, Cheng H. qPTMplants: an integrative database of quantitative post-translational modifications in plants. Nucleic Acids Research. 2021;50(D1):D1491-D1499. doi:10.1093/nar/gkab945. PMID:34718741. PMCID:PMC8728288.