QSDB

QSDB compiles published sensing and quenching interactions between organisms and signaling molecules in the human microbiome to support research on microbial quorum sensing.

Key Features:

• Comprehensive Data Collection: Compiles published interactions specifying organisms, signaling molecules, and whether the interaction is sensing or quenching.
• Human microbiome focus: Restricts entries to interactions reported within the human microbiome.
• Systems Biology Graphical Notation diagrams: Represents quorum-sensing pathways and interactions using Systems Biology Graphical Notation diagrams.
• Integration with other databases: Provides links to other relevant databases to enable cross-referencing of entries.

Scientific Applications:

• Study of microbial communication: Enables analysis of quorum-sensing networks and interspecies chemical signaling in the human microbiome.
• Gene regulation research: Supports investigation of how microbes regulate gene expression in response to population density.
• Health and disease investigations: Facilitates exploration of microbial behavior and quorum-sensing roles in health and disease contexts.

Methodology:

Compiled published literature to extract organism pairs, signaling molecules, and interaction types (sensing or quenching), and represented interactions using Systems Biology Graphical Notation diagrams.