QuickPed

QuickPed generates, visualizes, and analyzes pedigrees to assess familial relatedness, inbreeding, and kinship for genetics, epidemiology, and evolutionary biology.

Key Features:

• Interactive Pedigree Creation: Constructs and edits detailed multi-generation pedigrees interactively.
• Support for Complex Inbreeding: Handles consanguineous unions and complex multi-generation inbreeding scenarios.
• Rich Library of Pedigrees: Provides a comprehensive library of common and illustrative pedigree templates and examples.
• Advanced Relatedness Analysis: Calculates standard coefficients of relatedness, including inbreeding, kinship, and identity coefficients.
• Specialized Plots for Visualizing Relatedness: Produces plots that visually represent pairwise and group relatedness within pedigrees.
• Novel Algorithm for Describing Relationships: Implements an algorithm that generates verbal descriptions of pairwise relationships within pedigrees.

Scientific Applications:

• Geneticists: Quantify hereditary patterns and compute inbreeding and kinship coefficients in family-based genetic studies.
• Epidemiologists: Trace familial transmission patterns and assess relatedness in disease investigations involving families.
• Evolutionary biologists: Analyze kinship dynamics and inbreeding effects in population and pedigree-based evolutionary studies.

Methodology:

Implements a novel algorithmic approach to produce verbal descriptions of pairwise relationships and computational methods to calculate inbreeding, kinship, and identity coefficients and to generate relatedness plots.