QuickSNP

Gene-Centric SNP Selection Tool: Automated tagSNP Prioritization and Filtering

Gene-Centric SNP Selection Tool automates identification and prioritization of tagSNPs within specified chromosomal regions or genes based on gene-centric relevance, coding non-synonymous status, and inter-SNP distance constraints.

Key Features:

• Gene-Centric Selection Module: Selects SNPs located within or proximal to specified genes or chromosomal regions.
• Coding Non-Synonymous SNP Selection: Identifies SNPs causing amino acid changes in coding regions.
• Inter-SNP Distance Filtering: Filters SNPs by physical distance to reduce redundancy and optimize marker spacing.
• Genotyping Assay Annotation: Reports genotyping assay availability and inclusion on whole-genome genotyping chips.

Scientific Applications:

• Genetic Association Studies: Enables efficient SNP selection for association mapping and genotyping experiment design.

Methodology:

Applies automated algorithms and user-defined parameters to identify tagSNPs within input chromosomal regions or genes, prioritizing variants based on gene-centric location, non-synonymous coding potential, and inter-SNP distance criteria.