rBiopaxParser

rBiopaxParser parses and converts BioPAX level 2 and 3 files into R-accessible data structures to enable programmatic access, modification, regulatory graph generation, and pathway visualization for bioinformatics analyses.


Key Features:

  • Parsing Capabilities: Supports parsing of BioPAX levels 2 and 3 to read complex pathway data encoded in the BioPAX format.
  • Data Access and Modification: Provides functions to access and modify specific components of the BioPAX model within R data structures.
  • Regulatory Graph Generation: Generates regulatory graphs that depict controlling interactions within pathways.
  • Pathway Visualization: Produces visual representations of BioPAX pathways for analysis and dissemination.
  • Integration with R: Exposes BioPAX data inside the R environment to enable downstream statistical and bioinformatics analyses.

Scientific Applications:

  • Pathway Analysis: Enables analysis of biological pathways to investigate gene function, interactions, and regulatory mechanisms.
  • Data Integration: Facilitates integration of BioPAX pathway data with other genomics datasets for combined analyses.
  • Visualization and Presentation: Supports creation of detailed pathway diagrams for research reporting and interpretation.

Methodology:

Parses BioPAX (levels 2 and 3) files and converts them into R-accessible data structures for programmatic access, modification, regulatory graph generation, and visualization.

Topics

Collections

Details

License:
GPL-2.0
Tool Type:
command-line tool, library
Operating Systems:
Linux, Windows, Mac
Programming Languages:
R
Added:
1/17/2017
Last Updated:
1/9/2019

Operations

Data Inputs & Outputs

Publications

Kramer F, Bayerlová M, Klemm F, Bleckmann A, Beißbarth T. rBiopaxParser—an R package to parse, modify and visualize BioPAX data. Bioinformatics. 2012;29(4):520-522. doi:10.1093/bioinformatics/bts710. PMID:23274212.

Documentation

Downloads

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