rBiopaxParser
rBiopaxParser parses and converts BioPAX level 2 and 3 files into R-accessible data structures to enable programmatic access, modification, regulatory graph generation, and pathway visualization for bioinformatics analyses.
Key Features:
- Parsing Capabilities: Supports parsing of BioPAX levels 2 and 3 to read complex pathway data encoded in the BioPAX format.
- Data Access and Modification: Provides functions to access and modify specific components of the BioPAX model within R data structures.
- Regulatory Graph Generation: Generates regulatory graphs that depict controlling interactions within pathways.
- Pathway Visualization: Produces visual representations of BioPAX pathways for analysis and dissemination.
- Integration with R: Exposes BioPAX data inside the R environment to enable downstream statistical and bioinformatics analyses.
Scientific Applications:
- Pathway Analysis: Enables analysis of biological pathways to investigate gene function, interactions, and regulatory mechanisms.
- Data Integration: Facilitates integration of BioPAX pathway data with other genomics datasets for combined analyses.
- Visualization and Presentation: Supports creation of detailed pathway diagrams for research reporting and interpretation.
Methodology:
Parses BioPAX (levels 2 and 3) files and converts them into R-accessible data structures for programmatic access, modification, regulatory graph generation, and visualization.
Topics
Collections
Details
- License:
- GPL-2.0
- Tool Type:
- command-line tool, library
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- R
- Added:
- 1/17/2017
- Last Updated:
- 1/9/2019
Operations
Data Inputs & Outputs
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Publications
Kramer F, Bayerlová M, Klemm F, Bleckmann A, Beißbarth T. rBiopaxParser—an R package to parse, modify and visualize BioPAX data. Bioinformatics. 2012;29(4):520-522. doi:10.1093/bioinformatics/bts710. PMID:23274212.
PMID: 23274212