RDNAanalyzer

RDNAnalyzer: DNA Secondary Structure Prediction and Sequence Analysis

RDNAnalyzer predicts DNA secondary structures and performs comprehensive nucleotide sequence analysis using an extended Nussinov dynamic programming algorithm.


Key Features:

  • DNA Secondary Structure Prediction: Predicts DNA secondary structures and base pairings using an extended Nussinov dynamic programming algorithm.
  • Sequence Generation and Input: Generates random DNA sequences and processes user-provided sequences in RAW format.
  • DNA Replication Simulation: Simulates DNA replication processes.
  • Reverse Complement Generation: Computes reverse complementary DNA strands.
  • Transcription and Translation Simulation: Simulates transcription and translation to model gene expression processes.
  • Sequence Composition Analysis: Calculates total nucleotide count, ATGC base composition, and percentage distribution.
  • Sequence Cleaning: Cleans nucleotide sequences to ensure analytical accuracy.

Scientific Applications:

  • Genetic Regulation and Gene Expression Analysis: Supports investigation of DNA secondary structure, nucleic acid interactions, replication, transcription, and translation mechanisms.

Methodology:

Implements an extended Nussinov dynamic programming algorithm for DNA secondary structure prediction and integrates computational simulations of replication, reverse complementation, transcription, and translation with quantitative nucleotide composition analysis.

Topics

Details

Tool Type:
desktop application
Operating Systems:
Windows
Programming Languages:
C#
Added:
8/3/2017
Last Updated:
11/25/2024

Operations

Publications

Afzal M. RDNAnalyzer: A tool for DNA secondary structure prediction and sequence analysis. Bioinformation. 2012;8(14):687-690. doi:10.6026/97320630008687. PMID:23055611. PMCID:PMC3449372.

Documentation

Links