RDNAanalyzer
RDNAnalyzer: DNA Secondary Structure Prediction and Sequence Analysis
RDNAnalyzer predicts DNA secondary structures and performs comprehensive nucleotide sequence analysis using an extended Nussinov dynamic programming algorithm.
Key Features:
- DNA Secondary Structure Prediction: Predicts DNA secondary structures and base pairings using an extended Nussinov dynamic programming algorithm.
- Sequence Generation and Input: Generates random DNA sequences and processes user-provided sequences in RAW format.
- DNA Replication Simulation: Simulates DNA replication processes.
- Reverse Complement Generation: Computes reverse complementary DNA strands.
- Transcription and Translation Simulation: Simulates transcription and translation to model gene expression processes.
- Sequence Composition Analysis: Calculates total nucleotide count, ATGC base composition, and percentage distribution.
- Sequence Cleaning: Cleans nucleotide sequences to ensure analytical accuracy.
Scientific Applications:
- Genetic Regulation and Gene Expression Analysis: Supports investigation of DNA secondary structure, nucleic acid interactions, replication, transcription, and translation mechanisms.
Methodology:
Implements an extended Nussinov dynamic programming algorithm for DNA secondary structure prediction and integrates computational simulations of replication, reverse complementation, transcription, and translation with quantitative nucleotide composition analysis.
Topics
Details
- Tool Type:
- desktop application
- Operating Systems:
- Windows
- Programming Languages:
- C#
- Added:
- 8/3/2017
- Last Updated:
- 11/25/2024
Operations
Publications
Afzal M. RDNAnalyzer: A tool for DNA secondary structure prediction and sequence analysis. Bioinformation. 2012;8(14):687-690. doi:10.6026/97320630008687. PMID:23055611. PMCID:PMC3449372.