reb

reb identifies regional expression biases in high-throughput genomic datasets to characterize spatial patterns of gene expression across genomic regions.


Key Features:

  • Regional Expression Bias Identification: Detects biases in gene expression across genomic regions to reveal spatial patterns of gene activity.
  • High-throughput Data Support: Operates on high-throughput genomics and molecular biology datasets.
  • Integration with Bioconductor: Integrates with the Bioconductor project and interoperates with over 934 Bioconductor packages.
  • Quality Assurance: Subject to formal initial review and continuous automated testing by the Bioconductor community.

Scientific Applications:

  • Genomics Research: Enables discovery of spatial gene expression patterns relevant to genome organization and function.
  • Molecular Biology Studies: Supports analysis of region-specific expression changes to investigate regulatory mechanisms and disease-associated expression shifts.

Methodology:

Implemented in the statistical programming language R.

Topics

Collections

Details

License:
GPL-2.0
Tool Type:
command-line tool, library
Operating Systems:
Linux, Windows, Mac
Programming Languages:
R
Added:
1/17/2017
Last Updated:
11/25/2024

Operations

Publications

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.

Documentation

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