RNA editing database (REDIdb)

REDIdb: Database of Organellar RNA Editing Events

REDIdb curates and annotates RNA editing events in organelles, documenting nucleotide substitutions, insertions, and deletions that modify genetic messages post-transcriptionally across diverse species.

Key Features:

• Comprehensive Annotation: Records nucleotide substitutions, insertions, and deletions with detailed biological context specific to organelles.
• Clade-Specific Mechanisms: Captures diverse biochemical mechanisms of RNA editing across evolutionary lineages.
• Comparative Analysis: Enables comparison of RNA editing entries with external databases including dbRES and EdRNA.

Scientific Applications:

• Evolutionary Biology: Supports analysis of clade-specific RNA editing mechanisms and evolutionary adaptations.
• Molecular Genetics: Facilitates investigation of RNA editing effects on gene expression and organellar function.
• Bioinformatics and Computational Biology: Enables computational analyses of RNA editing patterns and processes.

Methodology:

Systematically curates RNA editing data from primary repositories including GenBank and annotates each entry with detailed organellar and biological context.