reformat_snpeff_for_syntview

reformat_snpeff_for_syntview converts tabular snpEff outputs into SynTView-compatible .snp and .indel files for downstream visualization and analysis of single nucleotide polymorphisms and insertions/deletions.


Key Features:

  • Conversion Capability: Parses tabular snpEff output and reformats variant annotations into .snp and .indel files compatible with SynTView.
  • Integration with Galaxy@Pasteur: Implemented for use within the Galaxy@Pasteur instance to leverage Galaxy's computational framework for reproducibility and traceability.
  • Execution via Galaxy API/Bioblend: Supports invocation through the Galaxy API or the Bioblend library to run on the Institut Pasteur compute cluster.

Scientific Applications:

  • Genetic Variation Analysis: Enables visualization and analysis of SNPs and indels in SynTView using snpEff annotations.
  • Metagenomic Data Integration: Integrates into Galaxy@Pasteur workflows that interface with services such as MetaGenSense for metagenomic variant analyses.

Methodology:

Processes tabular snpEff files to generate .snp and .indel outputs and executes within the Galaxy@Pasteur environment via the Galaxy API or the Bioblend library on the Institut Pasteur cluster.

Topics

Collections

Details

Maturity:
Mature
Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Added:
12/19/2016
Last Updated:
6/16/2020

Operations

Data Inputs & Outputs

Publications

Afgan E, Baker D, van den Beek M, Blankenberg D, Bouvier D, Čech M, Chilton J, Clements D, Coraor N, Eberhard C, Grüning B, Guerler A, Hillman-Jackson J, Von Kuster G, Rasche E, Soranzo N, Turaga N, Taylor J, Nekrutenko A, Goecks J. The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update. Nucleic Acids Research. 2016;44(W1):W3-W10. doi:10.1093/nar/gkw343. PMID:27137889. PMCID:PMC4987906.

Mareuil F, Doppelt-Azeroual O, Ménager H. A public Galaxy platform at Pasteur used as an execution engine for web services. Unknown Journal. 2017. doi:10.7490/f1000research.1114334.1.

Documentation

Links