REMS

REMS manages differential access to sensitive biomedical datasets by processing Data Access Applications and enforcing resource access entitlements to uphold confidentiality, consent restrictions, and legal governance.

Key Features:

• Data Access Application submission: Enables researchers to submit Data Access Applications for dataset access requests.
• Data Access Committee processing: Allows Data Access Committees to review and process applications to authorize or deny access.
• Digital identity federation: Implements a digital identity federation framework for authentication and federated identity management.
• Resource access entitlements: Manages resource access entitlements to enforce fine-grained permissions and access control across datasets.
• Open-source component configuration: Assembles common open-source software components configured to support differential access management across heterogeneous biomedical data repositories.
• Protected data support: Supports datasets ranging from publicly accessible to highly restricted pseudonymised patient information, addressing confidentiality, identifiability, consent scope, and data usage agreements.
• Pilot validation: Demonstrated feasibility and reproducibility of a secure infrastructure for managing sensitive biomedical data in a pilot implementation.
• Domain applicability: Applicable to biobanking and biosample research data governance.

Scientific Applications:

• Translational research governance: Governs access to sensitive human research data for translational researchers under consent and legal constraints.
• Biobanking and biosample access control: Manages access controls and governance for biobanking and biosample datasets.
• Controlled multi-repository sharing: Enables controlled data sharing across heterogeneous biomedical repositories with varying protection needs.
• Ethical and legal compliance enforcement: Supports enforcement of consent scope, confidentiality, identifiability restrictions, and data usage agreements.

Methodology:

Implements a digital identity federation framework and software for managing resource access entitlements, assembling common open-source components configured for differential access management, and processing Data Access Applications by Data Access Committees.