RiboDB

RiboDB provides a curated collection of ribosomal protein (r-protein) sequences from complete prokaryotic genomes to support prokaryotic systematics and evolutionary analyses.

Key Features:

• Comprehensive Coverage: Contains sequences of 90 distinct r-proteins derived from 3,750 complete prokaryotic genomes spanning 38 phyla/major classes and 1,759 species.
• Regular Updates: The database is updated weekly to incorporate newly available complete prokaryotic genomes.
• Curated Annotations: Provides curated and accurately annotated r-protein sequences to mitigate frequent misannotation or absence of r-protein annotations in genome records.
• r-Protein Focus: Emphasizes r-proteins as alternatives to ribosomal RNA (rRNA) for prokaryotic systematics and comparative analyses.

Scientific Applications:

• Prokaryotic Systematics and Evolutionary Biology: Enables comparative analyses of evolutionary relationships among prokaryotes using r-protein sequences.
• Phylogenetic Studies: Supports construction of phylogenetic trees and exploration of evolutionary patterns across prokaryotic lineages.
• Genomic Annotation Projects: Serves as a reference for annotating r-proteins in newly sequenced genomes to improve annotation accuracy.
• Functional Genomics: Provides sequence data for studies of r-protein roles and interactions within ribosomes.

Methodology:

Extraction and curation of r-protein sequences from complete prokaryotic genome sequences, with weekly database updates.