RmiR

RmiR integrates microRNA (miRNA) datasets with their target gene annotations using multiple databases within the Bioconductor R environment for downstream genomic analyses.


Key Features:

  • Integration Capabilities: Merges miRNA datasets with target genes using multiple databases to provide comprehensive coverage and improve annotation accuracy.
  • Bioconductor Framework: Operates within the Bioconductor project and uses the R statistical programming language for data processing and analysis.
  • Interoperability: Interoperable with other Bioconductor packages to enable incorporation into broader bioinformatics workflows.

Scientific Applications:

  • Genomic Research: Enables investigation of gene regulation mechanisms and the roles of miRNAs by combining miRNA and target gene information.
  • Molecular Biology Studies: Supports analysis of miRNA–target interactions to study molecular pathways and disease mechanisms.

Methodology:

Uses statistical programming in R to process and analyze high-throughput data, enabling data manipulation and visualization.

Topics

Collections

Details

License:
Artistic-2.0
Cost:
Free of charge
Tool Type:
command-line tool, library
Operating Systems:
Linux, Windows, Mac
Programming Languages:
R
Added:
1/17/2017
Last Updated:
11/25/2024

Operations

Publications

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.

Documentation

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