RNA
RNA aligns next-generation sequencing (NGS) nucleotide reads to a reference genome with high accuracy and computational efficiency to support downstream genomic analyses.
Key Features:
- Accurate NGS Read Alignment: Maps short nucleotide reads to reference genomes with high precision to ensure reliable coordinate assignment.
- Computational Efficiency: Optimizes alignment algorithms for reduced runtime on large-scale high-throughput sequencing datasets.
Scientific Applications:
- Genomic and Transcriptomic Analysis: Supports single nucleotide polymorphism (SNP) detection, gene expression quantification, and epigenomic analyses including DNA methylation and histone modification mapping.
Methodology:
The tool implements optimized sequence alignment algorithms to balance speed and accuracy when mapping NGS reads to reference genomes, enabling scalable processing of high-throughput sequencing data.
Topics
Details
- License:
- GPL-3.0
- Maturity:
- Mature
- Tool Type:
- desktop application
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- C++
- Added:
- 1/13/2017
- Last Updated:
- 11/25/2024
Operations
Publications
Vezzi F, Del Fabbro C, Tomescu AI, Policriti A. rNA: a fast and accurate short reads numerical aligner. Bioinformatics. 2011;28(1):123-124. doi:10.1093/bioinformatics/btr617. PMID:22084252.
PMID: 22084252
Documentation
General
http://erne.sourceforge.net/