RNA-combine

RNA-combine integrates and analyzes transcriptome data from Illumina, 10x Genomics, and PacBio platforms to provide comprehensive transcriptomic profiling, including quality assessment, differential expression, isoform quantification, and single-cell analysis.

Key Features:

• Multi-platform Support: Integrates transcriptome data from Illumina, 10x Genomics, and PacBio for comparative and integrated analyses.
• Comprehensive Analysis Modules: Implements ten analysis modules covering differential expression, isoform quantification, and single-cell profiling.
• Automated Workflow: Automates quality assessment and platform-specific processing to streamline progression from raw data to downstream analysis and result interpretation.
• Visualization Capabilities: Provides visualization tools for interpreting complex transcriptomic data.

Scientific Applications:

• Transcriptome Exploration: Analyzes gene expression at bulk and single-cell levels to investigate cellular heterogeneity, disease mechanisms, and developmental processes in oncology, immunology, and developmental biology.

Methodology:

Automated pipeline processes raw data, applies platform-specific steps, and uses analysis modules for differential expression, isoform quantification, and single-cell profiling.