RNAenrich

RNAenrich performs functional enrichment and interaction network analysis for mRNAs, microRNAs (miRNAs), long non-coding RNAs (lncRNAs), circular RNAs (circRNAs), small nucleolar RNAs (snoRNAs), and PIWI-interacting RNAs (piRNAs) in human and mouse.


Key Features:

  • Multi-RNA Enrichment Analysis: Conducts simultaneous pathway, functional, and disease enrichment analysis using experimentally validated RNA–target interaction datasets across coding and non-coding RNA types.
  • Interaction Network Construction: Generates ncRNA–target gene interaction networks based on millions of validated RNA–target interactions to support mechanistic interpretation.

Scientific Applications:

  • Non-Coding RNA Functional Characterization: Supports functional annotation and pathway analysis of miRNAs, lncRNAs, circRNAs, snoRNAs, and piRNAs in human and mouse studies.

Methodology:

RNAenrich integrates experimentally supported RNA–target gene interactions to map RNAs to associated pathways, biological functions, and diseases, and constructs corresponding interaction networks for enrichment analysis.

Topics

Details

License:
CC-BY-4.0
Cost:
Free of charge
Tool Type:
web application
Operating Systems:
Mac, Linux, Windows
Added:
12/30/2023
Last Updated:
11/24/2024

Operations

Publications

Zhang S, Amahong K, Zhang Y, Hu X, Huang S, Lu M, Zeng Z, Li Z, Zhang B, Qiu Y, Dai H, Gao J, Zhu F. RNAenrich: a web server for non-coding RNA enrichment. Bioinformatics. 2023;39(7). doi:10.1093/bioinformatics/btad421. PMID:37399102. PMCID:PMC10356780.

PMID: 37399102
Funding: - Natural Science Foundation of Zhejiang Province: LR21H300001 - National Natural Science Foundation of China: 22220102001, U1909208