RNAget

RNAget provides a standardized, secure API for programmatic access and slicing of genomic quantification matrices (including RNA-seq, microarray, ATAC-seq, and ChIP-seq) to enable gene expression and regulatory genomics analyses.

Key Features:

• Standardized Access Interface: Exposes a unified API for programmatic, secure retrieval of genomic quantification matrices.
• Matrix-Based Data Handling: Operates on expression matrix formats representing gene- or feature-level quantifications from RNA-seq, microarray, and other sequencing-based assays.
• Data Slicing Capabilities: Supports matrix slicing to extract specific subsets such as particular genes or conditions without retrieving full matrices.
• Generalizability Across Genomic Technologies: Applies to RNA-seq and microarray and generalizes to other sequence-based quantification technologies such as ATAC-seq and ChIP-seq.

Scientific Applications:

• Gene Expression Analysis: Enables retrieval and subsetting of RNA-seq and microarray quantifications for gene expression studies.
• Epigenetic Studies: Facilitates access to ATAC-seq quantification matrices for chromatin accessibility analyses.
• Protein-DNA Interaction Mapping: Supports access to ChIP-seq quantification matrices for studies of protein–DNA interactions and regulatory mechanisms.

Methodology:

Implements a secure API framework to provide programmatic access to genomic quantification matrices and supports matrix slicing to return selected subsets.