RNAget

RNAget provides secure, standardized programmatic access to genomic quantification matrices to enable sharing and analysis of RNA-seq, microarray, ATAC-seq, and ChIP-seq quantification data.


Key Features:

  • Standardized API: Provides a unified programmatic interface for secure, interoperable access to genomic quantification matrices.
  • Matrix data handling: Handles expression matrices from RNA-seq and microarray and supports slicing to extract specific subsets of rows and columns.
  • Sequencing technology coverage: Supports RNA quantification and extends to ATAC-seq and ChIP-seq quantification matrices.
  • Data security and access control: Implements secure access mechanisms and controls for confidential large-scale data sharing.

Scientific Applications:

  • Transcriptomic studies: Enables analysis of RNA-seq and microarray quantifications for gene expression and regulatory investigations.
  • Epigenetic research: Enables analysis of ATAC-seq and ChIP-seq quantifications for chromatin accessibility and protein–DNA interaction studies.
  • Data integration and sharing: Facilitates standardized integration, sharing, and reproducible analysis of genomic quantification datasets across platforms.

Methodology:

Implements a programmatic API architecture with parameterized matrix slicing and secure access controls for retrieval of genomic quantification matrices.

Topics

Details

Cost:
Free of charge
Tool Type:
api
Operating Systems:
Mac, Linux, Windows
Added:
10/1/2023
Last Updated:
11/24/2024

Operations

Publications

Upchurch S, Palumbo E, Adams J, Bujold D, Bourque G, Nedzel J, Graham K, Kagda MS, Assis P, Hitz B, Righi E, Guigó R, Wold BJ, Adams J, Brazma A, Bujold D, Burchard J, Capka J, Cherry M, Clarke L, Craft B, Dermitzakis M, Diekhans M, Dursi J, Fitzsimons MS, Flaming Z, Garrido R, Gil A, Godden P, Green M, Guigo R, Guttman M, Haas B, Haeussler M, Hitz B, Li B, Linnarsson S, Lipski A, Liu D, Longerich S, Lougheed D, Manning J, Marioni J, Meyer C, Montgomery S, Morrow A, Munoz-Power Fuentes A, Nedzel J, Nguyen D, Osborn K, Ouellette F, Palumbo E, Papatheodorou I, Pervouchine D, Ramani A, Rambla J, Sadjad B, Steinberg D, Talkar J, Tickle T, Tzeng K, Upchurch S, Vaisipour S, Watford S, Wold B, Zhang Z, Zhu J. RNAget: an API to securely retrieve RNA quantifications. Bioinformatics. 2023;39(4). doi:10.1093/bioinformatics/btad126. PMID:36897015. PMCID:PMC10081869.

PMID: 36897015
Funding: - Genome Canada/Génome Québec: 249333

Documentation