RNAInter

RNAInter aggregates and annotates RNA-associated interactions to support analysis of RNA–RNA, RNA–protein, RNA–DNA, and RNA–compound relationships across multiple species.

Key Features:

• RAID v2.0 expansion: An 8-fold increase in interaction data relative to RAID v2.0, incorporating interactions across 94 additional species.
• Coverage: Includes interactions involving over 450,000 unique molecules, comprising RNA, protein, DNA, and compounds.
• Enhanced annotations: Provides detailed annotations for RNA editing, localization, modification, structure, and homology interaction.
• Advanced functional tools: Supports fuzzy search, batch search, interaction network visualization, and RNA dynamic expression analysis.
• Embedded interactome tools: Integrates RIscoper, IntaRNA, PRIdictor, and DeepBind for specialized interaction analyses.

Scientific Applications:

• Interactome mapping: Enable comprehensive exploration and mapping of RNA interactomes across species.
• Regulatory network analysis: Support investigation of RNA-mediated regulatory landscapes, including RNA–RNA and RNA–protein interactions.
• Functional and disease studies: Facilitate identification of RNA–DNA and RNA–compound interactions relevant to biological processes and disease mechanisms.

Methodology:

Updated RAID v2.0 datasets with expanded interaction records and annotations (RNA editing, localization, modification, structure, homology interaction) and integrated RIscoper, IntaRNA, PRIdictor, and DeepBind.