RNAMST
RNAMST identifies homologs of predefined RNA structural motifs within large collections of RNA sequences, enabling analysis of RNA regulatory mechanisms including motifs implicated in post-translational regulation of gene expression.
Key Features:
- Efficient data preprocessing: Implements strategic data preprocessing that enhances search efficiency on large RNA sequence datasets.
- High-performance motif search: Integrates algorithms that deliver improved search speed and efficiency relative to earlier approaches.
- Flexibility in analysis: Supports analysis of known functional RNA elements and putative structural motifs.
Scientific Applications:
- Homolog discovery: Identification of homologous RNA structural motifs across large sequence collections.
- Study of RNA regulatory mechanisms: Enables investigation of RNA-mediated regulation of gene expression, including roles in post-translational regulation.
- Characterization of functional and putative motifs: Facilitates analysis and comparison of known functional RNA elements and candidate structural motifs.
Methodology:
Integration of advanced algorithms for data preprocessing and motif searching to achieve high accuracy and speed on large-scale RNA sequence databases.
Topics
Details
- Tool Type:
- web application
- Added:
- 3/24/2017
- Last Updated:
- 11/25/2024
Operations
Publications
Chang T, Huang H, Chuang T, Shien D, Horng J. RNAMST: efficient and flexible approach for identifying RNA structural homologs. Nucleic Acids Research. 2006;34(Web Server):W423-W428. doi:10.1093/nar/gkl231. PMID:16845040. PMCID:PMC1538813.