RNA virus genome database (RNAVirusDB)

RNA virus genome database (RNAVirusDB) compiles RNA virus genomic data and enables comparative analysis through sequence identification and whole-genome alignments.

Key Features:

• Genome Annotation and Alignment: Provides detailed RNA virus genome organization, translated genome sequences, and multiple whole-genome alignments for species with multiple fully sequenced isolates.
• Sequence Identification Tools: Accepts user-submitted nucleotide sequences and identifies matches within the database to support genomic characterization.

Scientific Applications:

• Comparative RNA Virus Genomics: Supports analysis of viral evolution, genetic diversity, pathogenicity, and host interactions through cross-species and strain-level genome comparisons.

Methodology:

RNAVirusDB aggregates curated RNA virus genome sequences, generates translated coding sequences and multiple whole-genome alignments, and implements sequence similarity searches to enable systematic comparative genomic analysis.