rNMPID
rNMPID database compiles and integrates genome-wide ribonucleotide monophosphate (rNMP) embedment data in genomic DNA from diverse rNMP-mapping techniques.
Key Features:
- Integrated rNMP-Mapping Datasets: Aggregates data from multiple rNMP-mapping methodologies, documenting strand bias, incorporation preferences, and genetic background–specific embedment patterns.
- Cross-Species Comparative Analysis: Includes datasets from multiple organisms to enable comparative analysis of rNMP incorporation patterns and evolutionary trends.
Scientific Applications:
- Genome Stability and Disease Research: Supports investigation of rNMP incorporation patterns in relation to genome stability, cellular processes, and disease associations including cancer.
Methodology:
The database systematically collects and standardizes genome-wide datasets generated by diverse rNMP-mapping techniques to catalog rNMP embedment sites and associated genomic features for integrative analysis.
Topics
Details
- License:
- AGPL-3.0
- Cost:
- Free of charge
- Tool Type:
- web application
- Operating Systems:
- Mac, Linux, Windows
- Programming Languages:
- Python
- Added:
- 6/18/2024
- Last Updated:
- 6/18/2024
Operations
Data Inputs & Outputs
Genotyping
Publications
Yang J, Sun M, Ran Z, Yang T, Kundnani DL, Storici F, Xu P. rNMPID: a database for riboNucleoside MonoPhosphates in DNA. Bioinformatics Advances. 2024;4(1). doi:10.1093/bioadv/vbae063. PMID:38736683. PMCID:PMC11088741.
PMID: 38736683
Funding: - National Institutes of Health: NIEHS R01 ES026243
- Howard Hughes Medical Institute Faculty Scholars Award: 55108574
- Mathers Foundation: AWD-002589