RobMixReg

RobMixReg implements robust mixture regression methods for identifying and modeling latent subgroups and unobserved heterogeneity in high-dimensional predictor settings while accommodating outliers and diverse regression forms.


Key Features:

  • Robustness: Handles outliers to stabilize parameter estimates and inference in the presence of anomalous data points.
  • Flexibility: Supports diverse regression forms to allow model specification tailored to different data-generating relationships.
  • High Dimensionality: Manages high-dimensional predictor spaces for analyses with large numbers of covariates.
  • Comprehensive Integration: Combines robustness, flexible regression forms, and high-dimensional modeling within a mixture regression framework.

Scientific Applications:

  • Latent subgroup analysis: Identifies and characterizes latent subgroups and unobserved heterogeneity within populations.
  • Genomics: Applies to genomics for detecting heterogeneity and subgroup structure in high-dimensional omics data.
  • Epidemiology: Applies to epidemiology for stratifying populations and modeling heterogeneous responses in observational studies.
  • Social sciences: Applies to social sciences for detecting latent classes and heterogeneous effects across subpopulations.

Methodology:

Implements finite mixture models to approximate general distribution functions in a semi-parametric manner and capture unobserved heterogeneity.

Topics

Details

License:
GPL-2.0
Programming Languages:
R
Added:
1/18/2021
Last Updated:
2/8/2021

Operations

Publications

Chang W, Wan C, Yu C, Yao W, Zhang C, Cao S. RobMixReg: an R package for robust, flexible and high dimensional mixture regression. Unknown Journal. 2020. doi:10.1101/2020.08.02.233460.