Rodent Genome and Pathogen Atlas

Rodent Genome and Pathogen Atlas integrates rodent genomics, pathogen sequences, and epidemiological profiles to facilitate comparative genomic analysis and pathogen exploration within rodent species for biomedical research.

Key Features:

• Species Database: Provides basic information on 2706 rodent species.
• Genome Visualization and Comparison: Offers chromosome-level visualization of genomes, functional annotations, and genomic comparisons across 121 rodent species.
• Pathogen Epidemiological Profiles: Compiles epidemiological profiles based on 21852 pathogen sequences reported in rodents.
• Multi-Omics Analytical Tools: Includes genomic tools for in-depth exploration of rodent multi-omics.

Scientific Applications:

• Biomedical Model Development: Advances the development of biomedical models for humans to promote public health.
• Rodent Genetics and Evolution: Innovates research in genetics, genomics, and molecular evolution in rodents.
• Zoonotic Disease Research: Offers knowledge on rodent-borne emerging and re-emerging zoonotic infectious diseases.
• Host-Pathogen Interaction Studies: Supports investigation of host-pathogen interactions and arms race evolution.
• Environmental Adaptation Research: Enables study of adaptations to environment or climate change in rodents.
• Complex Phenotype Analysis: Facilitates exploration of molecular underpinnings of intriguing complex phenotypes in rodents.

Methodology:

The atlas integrates genomic variations among rodents with information on rodent-borne pathogens through a systematic framework for comparative analysis.