RPINBASE

RPINBASE extracts structural features for RNA–protein interaction (RPI) prediction to support machine learning model development.


Key Features:

  • Structural Feature Extraction: Generates feature sets for both positive and negative RNA–protein interaction samples to enable supervised machine learning training.
  • Nested Query-Based Data Retrieval: Implements an efficient nested query system to accelerate feature generation and dataset construction.

Scientific Applications:

  • Machine Learning–Based RPI Prediction: Supports development of predictive models for RNA–protein interactions, including applications such as aptamer design.

Methodology:

RPINBASE applies nested query strategies to retrieve and construct structural feature representations of RNA–protein interaction datasets, generating labeled positive and negative samples for downstream machine learning classification.

Topics

Details

Added:
1/18/2021
Last Updated:
2/8/2021

Operations

Publications

Torkamanian-Afshar M, Lanjanian H, Nematzadeh S, Tabarzad M, Najafi A, Kiani F, Masoudi-Nejad A. RPINBASE: An online toolbox to extract features for predicting RNA-protein interactions. Genomics. 2020;112(3):2623-2632. doi:10.1016/j.ygeno.2020.02.013. PMID:32092438.