RPS

RPS provides a curated repository of RNAs involved in liquid-liquid phase separation (LLPS) to support analysis of RNA roles in membraneless organelles.

Key Features:

• Comprehensive RNA Collection: Contains 21,613 LLPS-related RNAs from eukaryotes and viruses across 20 biomolecular condensates, categorized as 'Reviewed', 'High-throughput', and 'Predicted'.
• Detailed Annotations: Annotates sequence features, structural characteristics, RNA-protein and RNA-RNA interactions, and RNA modifications relevant to LLPS.
• Disease Associations: Includes disease annotations linking specific LLPS-related RNAs to pathological contexts.

Scientific Applications:

• Basic Research: Supports studies of the mechanisms by which RNAs contribute to the formation and regulation of membraneless organelles.
• Disease Mechanism Exploration: Enables identification and analysis of LLPS-related RNAs implicated in disease pathogenesis.
• Systems Biology Approaches: Facilitates integrative analyses combining LLPS RNA data with other omics datasets for systems-level investigation.

Methodology:

No computational methods or data-processing steps were specified in the provided description.