RRE
RRE extracts non-coding regions associated with annotated genes from genomic datasets to enable analysis of regulatory elements and post-transcriptional control.
Key Features:
- Non-Coding Region Extraction: Extracts gene upstream regions, 5′-untranslated regions (5′-UTRs), introns, 3′-untranslated regions (3′-UTRs), and downstream regions associated with annotated genes.
- Integration with NCBI Datasets: Leverages annotated genomic datasets available at the National Center for Biotechnology Information (NCBI) for extraction targets.
- Parser-Based Processing: Provides a parser for programmatic extraction of specified non-coding regions from annotated genomic data.
Scientific Applications:
- Gene Regulation Studies: Enables identification and analysis of regulatory elements in upstream and untranslated regions that influence gene activity.
- Expression Analysis: Supports analyses that correlate non-coding region features with gene expression patterns.
- Functional Genomics: Facilitates characterization of non-coding elements in functional genomics investigations.
- Alternative Splicing Investigation: Allows retrieval of intronic regions to investigate alternative splicing events.
- Post-Transcriptional Control Studies: Enables examination of 5′-UTRs and 3′-UTRs for roles in post-transcriptional regulation.
Methodology:
Uses a parser to process annotated genomic datasets, including datasets from NCBI, to extract specified non-coding regions.
Topics
Details
- Tool Type:
- command-line tool
- Operating Systems:
- Linux, Windows
- Programming Languages:
- Java
- Added:
- 12/18/2017
- Last Updated:
- 12/10/2018
Operations
Publications
Lazzarato F, Franceschinis G, Botta M, Cordero F, Calogero RA. RRE: a tool for the extraction of non-coding regions surrounding annotated genes from genomic datasets. Bioinformatics. 2004;20(16):2848-2850. doi:10.1093/bioinformatics/bth287.