RSCanner

RSCanner scans RNA transcripts to assess and map RNA secondary-structure content across large sequences for identification and prioritization of structural modules.

Key Features:

• Automated scanning: Automates scanning of entire RNA transcripts to identify regions with high secondary-structure content.
• Classification and propensity analysis: Classifies identified regions by propensity to adopt stable or dynamic secondary-structure configurations.
• Heatmap visualization: Produces heatmaps representing the density and distribution of RNA secondary structures across transcripts.

Scientific Applications:

• Functional genomics: Supports analysis of RNA structure–function relationships in functional genomics studies.
• Structural biology: Aids structural biology investigations aimed at elucidating RNA folding patterns and structural modules.
• Transcriptomic analysis: Provides detailed secondary-structure insights for transcriptomic analyses of large-scale RNA datasets.

Methodology:

Scans entire RNA transcripts and employs algorithms to detect regions with significant structural content, then classifies these regions based on structural stability.