rtdsm

rtdsm generates dose-surface maps (DSMs) from DICOM radiotherapy data to enable spatial analysis of dose distributions for hollow organs in dose–outcome studies.

Key Features:

• DSM calculation: Computes DSMs from DICOM RT data to represent spatial dose distributions on hollow-organ surfaces.
• User customizability: Provides configurable parameters to adjust DSM calculations and analysis settings for specific study requirements.
• Equivalent dose conversions: Performs conversions between dose metrics to enable comparisons across different treatment plans or studies.
• DSM feature extraction: Extracts common DSM-derived features used to quantify spatial dose patterns and identify radiosensitive subregions.
• DSM accumulation: Accumulates DSMs to support longitudinal analyses and comparative studies.
• DSM slicing methods: Implements planar and noncoplanar slicing approaches to generate alternative DSM representations.

Scientific Applications:

• Dose–outcome studies: Enables analysis of spatial dose distributions when correlating delivered dose with clinical outcomes.
• Radiosensitive subregion identification: Supports detection of spatially localized regions of sensitivity within hollow organs using DSM features.
• Inter-treatment comparison: Facilitates comparison of DSMs across different treatment plans or modalities via equivalent dose conversions and DSM metrics.
• Longitudinal and comparative analyses: Allows accumulation and comparison of DSMs over time or between cohorts for longitudinal studies.

Methodology:

Implementation and testing of two DSM slicing methods—planar and noncoplanar—to assess their effects on output DSMs.