Rtivity

Rtivity analyzes activity, sleep, and rhythmic behavior from infrared-based activity monitor data to quantify survival and behavioral parameters across multiple animal species.


Key Features:

  • Species-Specific Customization: Allows customization of analysis parameters for different species such as zebrafish, daphnia, and ants.
  • Implementation and Integration: Implemented in R and integrates with the Rethomics package.
  • Behavioral Metrics and Survival Analysis: Automates assessment of survival rates and computes parameters related to activity, sleep, and biological rhythms.
  • Fractal Analysis: Performs fractal analysis on activity fluctuations to characterize temporal patterns.
  • Analysis Scope: Analyzes circadian and non-circadian behaviors as well as stimulus responses.
  • Data Output: Generates graphs and exports structured datasets compatible with common statistical software.

Scientific Applications:

  • Ecology: Enables behavioral studies in ecological contexts to investigate organismal responses and interactions.
  • Neurobiology: Supports analysis of sleep and rhythmicity relevant to neural function and dysfunction.
  • Toxicology: Facilitates assessment of behavioral effects of toxicants on survival and activity patterns.
  • Pharmacology: Supports evaluation of behavioral responses to pharmacological compounds.
  • High-throughput small-organism studies: Supports high-throughput experiments using infrared-based activity monitors for small organisms.

Methodology:

Implemented in R with integration of the Rethomics package; processes data from infrared-based activity monitors; automates survival assessment; computes activity, sleep, and rhythmicity parameters; performs fractal analysis on activity fluctuations; and generates graphs and exports structured datasets, with species-specific parameter customization.

Topics

Details

License:
Not licensed
Cost:
Free of charge
Tool Type:
web application
Operating Systems:
Mac, Linux, Windows
Programming Languages:
R
Added:
7/4/2022
Last Updated:
11/24/2024

Operations

Publications

Silva RFO, Pinho BR, Monteiro NM, Santos MM, Oliveira JMA. Automated analysis of activity, sleep, and rhythmic behaviour in various animal species with the Rtivity software. Scientific Reports. 2022;12(1). doi:10.1038/s41598-022-08195-z. PMID:35264711. PMCID:PMC8907194.

PMID: 35264711
PMCID: PMC8907194
Funding: - Fundação para a Ciência e a Tecnologia: DL57/2016/CP1346/CT0016, PTDC/CTA-AMB/31544/2017

Links