rTRMui
rTRMui identifies transcriptional regulatory modules from high-throughput genomic and molecular biology data using the rTRM methodology.
Key Features:
- rTRM methodology: Implements the rTRM approach to identify transcriptional regulatory modules.
- High-throughput data analysis: Supports analysis of high-throughput genomic and molecular biology data for investigation of gene expression and regulation.
- Bioconductor integration: Leverages the Bioconductor ecosystem and its 934 interoperable packages for bioinformatics and statistical analyses.
Scientific Applications:
- Genomics and molecular biology: Enables inference of transcriptional regulatory networks and module-level regulators from high-throughput datasets.
- Interdisciplinary research: Facilitates integration of bioinformatics and statistical analysis within the Bioconductor framework for collaborative genomic studies.
Methodology:
Implements the rTRM methodology within the R programming language and leverages Bioconductor's ecosystem of 934 interoperable packages.
Topics
Collections
Details
- License:
- GPL-3.0
- Tool Type:
- command-line tool, library
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- R
- Added:
- 1/17/2017
- Last Updated:
- 11/25/2024
Operations
Publications
Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.