SANCDB

SANCDB catalogs natural chemical compounds derived from South African biodiversity to support drug discovery and chemoinformatics research.

Key Features:

• Comprehensive Repository: Contains a total of 1012 natural compounds, with 412 additional entries added since its inception.
• Chemical file formats: Supports multiple chemical file formats for download and integration into analysis workflows.
• Commercial analog links: Provides direct links to commercially available analogs in Mcule and MolPort to facilitate access to purchasable compounds.

Scientific Applications:

• Drug Discovery: Serves as a resource for hit identification and exploration of natural product scaffolds in drug discovery.
• Machine Learning Models: Functions as training data for machine learning models in chemoinformatics and predictive analyses.
• Database Integration: Contributes content that is incorporated into larger chemical databases to expand available chemical information.

Methodology:

Continuously updates the repository with newly reported compounds and integrates links to Mcule and MolPort to provide commercially available analogs.