Sapporo-web

Sapporo-web provides a unified execution platform for running and sharing bioinformatics workflows to support Whole Exome Sequencing (WES) and other high-throughput DNA sequencing analyses.

Key Features:

• Unified Workflow Execution Layer: Bridges multiple workflow systems to enable execution of workflows across heterogeneous execution environments.
• Support for Multiple Workflow Languages: Supports Common Workflow Language (CWL), Workflow Description Language (WDL), Snakemake, and Nextflow.
• API-Driven Architecture: Implements an API-driven architecture adhering to the Workflow Execution Service (WES) API standard proposed by the Global Alliance for Genomics and Health (GA4GH).
• Extensible and Scalable Design: Built with an extensible architecture to support future enhancements and scalable computation for high-throughput sequencing workloads.

Scientific Applications:

• Whole Exome Sequencing (WES) workflows: Executes and manages WES analysis workflows across supported workflow languages and execution backends.
• High-throughput DNA sequencing: Supports processing pipelines for high-throughput DNA sequencing data implemented in CWL, WDL, Snakemake, or Nextflow.
• Cross-system workflow sharing: Enables sharing and execution of workflows across different systems to achieve interoperability between workflow descriptions and execution environments.

Methodology:

Integrates CWL, WDL, Snakemake, and Nextflow via an API-driven architecture that implements the GA4GH Workflow Execution Service (WES) API standard.