scRNABatchQC
scRNABatchQC is an R package for simultaneously assessing the quality and consistency of multiple single-cell RNA sequencing (scRNA-seq) datasets. Single-cell RNA sequencing is a powerful technique for studying cellular heterogeneity, but the data can be affected by technical artifacts and biological variations. Distinguishing between these two factors is crucial for accurate data interpretation.
While existing tools can detect and remove low-quality cells within a single dataset, scRNABatchQC fills a gap by comparing multiple datasets across various technical and biological features, allowing researchers to identify systematic biases, batch effects, and outliers that may confound the analysis.
Topic
RNA-Seq;Transcriptomics
Detail
Operation: Validation
Software interface: Command-line user interface
Language: R
License: GNU Lesser General Public License v3.0
Cost: Free of charge with restrictions
Version name: v0.10.3
Credit: National Cancer Institute.
Input: -
Output: -
Contact: Yu Shy yu.shyr@vanderbilt.edu
Collection: -
Maturity: -
Publications
- scRNABatchQC: multi-samples quality control for single cell RNA-seq data.
- Liu Q, et al. scRNABatchQC: multi-samples quality control for single cell RNA-seq data. scRNABatchQC: multi-samples quality control for single cell RNA-seq data. 2019; 35:5306-5308. doi: 10.1093/bioinformatics/btz601
- https://doi.org/10.1093/bioinformatics/btz601
- PMID: 31373345
- PMC: PMC6954654
Download and documentation
Source: https://github.com/liuqivandy/scRNABatchQC/releases/tag/v0.10.3
Documentation: https://github.com/liuqivandy/scRNABatchQC/blob/master/README.md
Home page: https://github.com/liuqivandy/scRNABatchQC
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