scan-x

scan-x identifies sequence motifs and predicts post-translational modification (PTM) sites—including phosphorylation across human, mouse, fly, and yeast proteomes and acetylation in the human proteome—by integrating proteomic mass spectrometry data.

Key Features:

• Motif identification: Performs motif scans within sequence datasets to detect candidate PTM motifs.
• Proteomic mass spectrometry integration: Integrates extensive proteomic mass spectrometry data to inform and support PTM site prediction.
• PTM-specific predictions: Predicts phosphorylation sites across human, mouse, fly, and yeast proteomes and acetylation sites in the human proteome.
• Large-scale data analysis: Conducts large-scale scans using comprehensive datasets from multiple species.
• High specificity predictions: Produces high-specificity predictions for acetylation and phosphorylation sites.

Scientific Applications:

• Proteomic research: Identification of PTM sites to study protein function regulation and cellular processes.
• Comparative biology: Cross-species analysis of proteomic modifications across human, mouse, fly, and yeast proteomes.
• Drug discovery and development: Characterization of PTM sites to inform potential regulatory mechanisms relevant to therapeutic targeting.

Methodology:

Performs motif scanning of sequence datasets and integrates proteomic mass spectrometry data to predict post-translational modification sites.