Scribl

Scribl provides a canvas-based JavaScript library for web-based visualization and analysis of coordinate-based genomic data, including genomic features, DNA sequences, and genetic variants.

Key Features:

• Canvas-based HTML5 graphics: Implements an HTML5 canvas graphics library in JavaScript for rendering coordinate-based genomic visualizations.
• Coordinate-based data support: Visualizes genomic features, DNA sequences, and genetic variants mapped to genomic coordinates.
• Remote and large-scale data integration: Enables interaction with remotely hosted and large-scale genomic datasets, including cloud-hosted resources.
• Genomic data types: Supports visualization of genomic regions, read alignments, assembly data, and variant calls.
• Customization and extensibility: Provides programmatic hooks to create customized data views and analyses tailored to specific biological questions.

Scientific Applications:

• Integrative visualization of sequencing data: Visualizes read alignments and variant calls for interpretation of high-throughput sequencing experiments.
• Annotation and assembly inspection: Examines genomic annotations, assembly data, and genomic regions for genomic analyses.
• Custom analyses for specialized questions: Enables development of bespoke visual analyses tailored to specific research needs in genomics.

Methodology:

Implemented as a canvas-based HTML5 graphics library in JavaScript to render coordinate-based genomic features and integrate remotely hosted genomic datasets.