SEEK

SEEK enables the cataloguing, sharing, and management of heterogeneous scientific research datasets, models, simulations, experimental processes, and outcomes to support integration and analysis in systems biology.

Key Features:

• Access-Controlled Environment: Provides access-controlled sharing and exchange of data and models for collaborative work and public dissemination.
• Plug-in Architecture: Supports a configurable architecture linking experiments, protocols, data, models, and results to enable customizable workflows.
• Data Management Tools: Includes tools for running model simulations, plotting experimental data, and assisting with data annotation and standardization.
• Semantic Web Integration: Uses semantic web technologies to extract and serve metadata in RDF (Resource Description Format) and enable semantic queries across Linked Open Data.

Scientific Applications:

• Systems-level data integration: Integration of heterogeneous datasets and computational models to support systems-level modeling and prediction of biological processes.
• SysMO Consortium: Supports Systems Biology for Micro-organisms by facilitating integration of various omics datasets and models for microbial systems biology research.
• VLN (Virtual Liver Network): Links liver-related biological data and models to support collaborative research on liver function and disease.

Methodology:

Linking experiments, protocols, data, models, and results; running model simulations; plotting experimental data; assisting with data annotation and standardization; extracting and serving metadata in RDF (Resource Description Format) for semantic queries and integration with Linked Open Data.