SEISMICgraph

SEISMICgraph supports RNA structure research by offering data visualization and analysis capabilities for chemical probing modalities.

Key Features:

• Cross-condition comparison: Enables simultaneous comparison of data across different sequences and experimental conditions.
• Chemical probing visualization: Provides data visualization and analysis for a variety of chemical probing modalities.
• Rapid structural change visualization: Rapidly visualizes adenine-dependent structural changes and assesses the impact of pseudouridylation on these transitions.

Scientific Applications:

• Riboswitch investigation: Facilitates investigation of known and putative riboswitches.
• RNA modification analysis: Explores how RNA modifications influence RNA structure and binding.

Methodology:

The publication demonstrates utility by investigating known and putative riboswitches and exploring how RNA modifications influence their structure and binding.