ShinySyn
ShinySyn visualizes synteny and chromosome collinearity across genomes to support comparative genomics analyses.
Key Features:
- Interactive visualization: Dynamic visualization of macro-synteny and micro-synteny showing synteny blocks and gene pairs within and between species.
- Dynamic zooming: Seamless transition from genome-wide (macro-synteny) views to detailed gene-level representations of homologous genes.
- Genome-level dot plots: Generation of genome-wide dot plots to display chromosomal arrangements and conserved regions across entire genomes.
- MCscan integration: Built on the MCscan framework to perform collinearity and synteny detection analyses.
Scientific Applications:
- Comparative genomics: Investigation of chromosome collinearity and gene conservation across species.
- Evolutionary analysis: Exploration of evolutionary relationships and identification of conserved genomic regions.
- Structural variation analysis: Detection and interpretation of structural variations through synteny patterns.
- Plant genomics: Application of synteny analysis to plant genome studies.
Methodology:
Built on the MCscan framework and leveraging established MCscan algorithms for synteny detection.
Topics
Details
- License:
- MIT
- Cost:
- Free of charge
- Tool Type:
- command-line tool
- Operating Systems:
- Mac, Linux, Windows
- Programming Languages:
- R
- Added:
- 9/28/2022
- Last Updated:
- 11/24/2024
Operations
Publications
Xiao Z, Lam H. ShinySyn: a Shiny/R application for the interactive visualization and integration of macro- and micro-synteny data. Bioinformatics. 2022;38(18):4406-4408. doi:10.1093/bioinformatics/btac503. PMID:35866686.
PMID: 35866686
Funding: - Hong Kong Research Grants Council Area of Excellence Scheme: AoE/M-403/16