ShinySyn

ShinySyn visualizes synteny and chromosome collinearity across genomes to support comparative genomics analyses.


Key Features:

  • Interactive visualization: Dynamic visualization of macro-synteny and micro-synteny showing synteny blocks and gene pairs within and between species.
  • Dynamic zooming: Seamless transition from genome-wide (macro-synteny) views to detailed gene-level representations of homologous genes.
  • Genome-level dot plots: Generation of genome-wide dot plots to display chromosomal arrangements and conserved regions across entire genomes.
  • MCscan integration: Built on the MCscan framework to perform collinearity and synteny detection analyses.

Scientific Applications:

  • Comparative genomics: Investigation of chromosome collinearity and gene conservation across species.
  • Evolutionary analysis: Exploration of evolutionary relationships and identification of conserved genomic regions.
  • Structural variation analysis: Detection and interpretation of structural variations through synteny patterns.
  • Plant genomics: Application of synteny analysis to plant genome studies.

Methodology:

Built on the MCscan framework and leveraging established MCscan algorithms for synteny detection.

Topics

Details

License:
MIT
Cost:
Free of charge
Tool Type:
command-line tool
Operating Systems:
Mac, Linux, Windows
Programming Languages:
R
Added:
9/28/2022
Last Updated:
11/24/2024

Operations

Publications

Xiao Z, Lam H. ShinySyn: a Shiny/R application for the interactive visualization and integration of macro- and micro-synteny data. Bioinformatics. 2022;38(18):4406-4408. doi:10.1093/bioinformatics/btac503. PMID:35866686.

PMID: 35866686
Funding: - Hong Kong Research Grants Council Area of Excellence Scheme: AoE/M-403/16

Links