showalign WS (husar)

showalign WS (husar) displays aligned sets of protein and nucleic acid sequences in a publication-ready format for sequence analysis and interpretation.

Key Features:

• Alignment Display: Presents aligned biological sequences (proteins and nucleic acids) in a publication-ready format.
• Workflow Composition: Automatically composes workflows from bioinformatics services, synthesizing domain knowledge from resources such as EMBOSS.
• Semantic Service Composition (Bio-jETI): Employs semantic methodologies within the Bio-jETI workflow management system to enable automatic service composition.
• Domain Modeling: Utilizes manually defined and automatically derived semantic descriptions to recognize connections between services.

Scientific Applications:

• Sequence Analysis: Supports comparative genomics, phylogenetic studies, and functional annotation of genes and proteins through publication-ready alignments.
• Integrated Workflow Automation: Enables automatic composition of integrated analyses across multiple bioinformatics tools such as EMBOSS for complex research questions.
• Semantic Web Integration: Facilitates creation of machine-readable service descriptions to enhance automated access and integration of biological data.

Methodology:

Implements Semantic Web methodologies to create machine-readable service descriptions; uses semantic service composition as employed in Bio-jETI; synthesizes domain knowledge from resources like EMBOSS for automatic workflow composition; and applies manual and automatic semantic descriptions for domain modeling.