sigaR
sigaR performs joint analysis of high-throughput data across multiple molecular levels for integrative genomics and molecular biology research.
Key Features:
- Interoperability: Integrates with Bioconductor packages to enable combined analysis with other Bioconductor tools.
- Data Manipulation: Provides functions for manipulating complex objects derived from high-throughput experiments.
- Diverse Analytical Capabilities: Supports a variety of analysis types including statistical analyses for large-scale biological datasets.
- Visualization: Includes visualization functionalities for graphical representation of analysis results.
Scientific Applications:
- Interdisciplinary research: Facilitates collaborations between computational scientists and biologists by enabling joint analysis of multi-level molecular data.
- Genomic studies: Supports integration of diverse data types for genomics investigations.
- Molecular biology investigations: Enables comprehensive analysis pipelines for molecular biology experiments.
- Method development: Serves as a platform for developing and evaluating new bioinformatics methodologies.
Methodology:
sigaR runs within the R programming environment and uses Bioconductor packages that undergo formal initial review and continuous automated testing.
Topics
Collections
Details
- License:
- GPL-2.0
- Tool Type:
- command-line tool, library
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- R
- Added:
- 1/17/2017
- Last Updated:
- 11/25/2024
Operations
Data Inputs & Outputs
Differential gene expression analysis
Publications
Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.