SIMPA

SIMPA simulates light and sound interactions in biological tissues to generate realistic optical and acoustic images for developing and validating imaging forward models and data-driven methods.

Key Features:

• Modular Design: A modular architecture allows interchangeable module implementations and abstraction from concrete forward model implementations.
• Comprehensive Libraries: Includes libraries of biological structures (e.g., vessels) with associated optical and acoustic properties for constructing realistic tissue models.
• Simulation Pipeline Customization: Customizable pipelines integrate computational forward models, data processing algorithms, and digital device twins to produce end-to-end simulations.
• Data-Driven Approaches Support: Produces high-quality simulations across a range of wavelengths to support development and training of data-driven biomedical imaging methods.

Scientific Applications:

• Optical and Acoustic Imaging Research: Enables simulation-based studies across optical and acoustic imaging modalities to investigate imaging system behavior.
• Photoacoustic Imaging: Supports simulation and evaluation of photoacoustic imaging setups and forward models.
• Inverse Problem Development and Validation: Provides realistic simulated ground truth for development and validation of inverse problem algorithms.
• Tissue Property Studies: Facilitates exploration of how tissue optical and acoustic properties affect image formation.

Methodology:

Computational forward models simulate light and sound interactions with biological tissues within a modular pipeline; simulation outputs are processed by data processing algorithms and digital device twins to generate images.