SinusCor

SinusCor analyzes heart rate variability (HRV) from RR intervals to assess cardiac autonomic function.

Key Features:

• Comprehensive time and frequency metrics: Provides time-domain indices RMSSD and SDNN and frequency-domain indices LF, HF and the LF/HF ratio for interpreting cardiac autonomic function.
• Non-stationary data handling: Handles non-stationary RR intervals using moving segments for RMSSD and time-frequency analysis to capture dynamic HRV changes.
• Signal processing methods: Implements Fast Fourier Transform (FFT) and Autoregressive (AR) models for frequency-domain analysis of stationary data.
• Validation and reliability: Validated against Kubios v 3.0.1 with reported comparative indices (e.g., RMSSD: 93.96 ms, SDNN: 101.29 ms).

Scientific Applications:

• Cardiac autonomic research: Supports research and clinical studies focused on cardiac autonomic function using HRV metrics.
• Exercise and stress testing: Applicable to tilt tests, exercise, and other provocations that induce non-stationary HRV.
• Clinical assessment of autonomic responses: Enables assessment of autonomic responses in various health conditions.

Methodology:

Uses classical time-domain and frequency-domain analyses; moving segments for RMSSD; Fast Fourier Transform (FFT) and Autoregressive (AR) models for stationary data; and time-frequency analysis for non-stationary conditions.