sizepower
sizepower performs sample size and power calculations for microarray experimental studies within the Bioconductor ecosystem.
Key Features:
- Diverse calculation types: Supports five distinct types of sample size and power calculations adaptable to standard microarray experimental designs.
- Bioconductor and R integration: Implements computations within the Bioconductor ecosystem using the statistical programming capabilities of R for interoperability with other Bioconductor packages.
- Statistical foundation: Bases calculations on established statistical principles tailored for high-throughput genomic (microarray) data.
- Design adaptability: Accommodates various experimental designs commonly encountered in microarray studies.
Scientific Applications:
- Study planning: Determines appropriate sample sizes during the planning stages of microarray experiments to ensure adequate statistical power.
- Power and effect assessment: Assesses statistical power and the ability to detect meaningful biological differences in high-throughput microarray data, supporting resource optimization.
Methodology:
Calculations are performed using established statistical principles tailored for high-throughput genomic (microarray) data within the Bioconductor/R framework.
Topics
Collections
Details
- License:
- GPL-3.0
- Tool Type:
- command-line tool, library
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- R
- Added:
- 1/17/2017
- Last Updated:
- 11/25/2024
Operations
Publications
Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.