slimr

slimr integrates SLiM 3.0 with R to run population genomic simulations informed by empirical genetic and ecological data.


Key Features:

  • Seamless Integration: Connects SLiM 3.0 with the R environment to execute simulations and exchange data between SLiM and R.
  • Data Handling: Supports reading and cleaning empirical datasets in R and constructing empirically based parameters and initial conditions for simulations.
  • Simulation Capabilities: Leverages SLiM 3.0 to simulate complex evolutionary processes across space and time.
  • Result Retrieval and Analysis: Retrieves SLiM output in formats suitable for comparison with empirical data and enables analysis and visualization using R.
  • Pipeline Construction: Enables building integrated workflows that combine data preparation, simulation execution, and result analysis within R.

Scientific Applications:

  • Evolutionary and Ecological Inference: Integrates genetic and ecological data with simulations to study interactions between ecological and evolutionary processes.
  • Scenario Exploration: Enables exploration of scenarios that are difficult or impossible to observe directly in nature by running empirically informed simulations.
  • Landscape Population Genomics: Applied in landscape population genomics studies, including analyses such as those on desert mammals.

Methodology:

Reading and cleaning empirical data within R; using empirical data to construct simulation parameters and initial conditions; running simulations via SLiM 3.0 from R; employing R's analysis and visualization tools to compare simulation outputs with empirical datasets.

Topics

Details

License:
Other
Cost:
Free of charge
Tool Type:
library
Operating Systems:
Mac, Linux, Windows
Programming Languages:
R
Added:
12/13/2021
Last Updated:
12/13/2021

Operations

Publications

Dinnage R, Sarre SD, Duncan RP, Dickman CR, Edwards SV, Greenville A, Wardle G, Gruber B. slimr: An R package for integrating data and tailor-made population genomic simulations over space and time. Unknown Journal. 2021. doi:10.1101/2021.08.05.455258.

Documentation

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