SMARTER Database

SMARTER Database integrates SNP array datasets for sheep and goat breeds, standardizing genomic data and metadata to facilitate genetic diversity analyses.

Key Features:

• Data Harmonization: Harmonizes genotypes for about 12,000 sheep and 6,000 goats to a uniform coding and assembly version.
• Genotype Filtering: Provides tools for efficient filtering and selection of samples from the harmonized dataset.
• Data Access: Genotype data is accessible via File Transfer Protocol, and metadata can be interacted with through custom scripts.

Scientific Applications:

• Genetic Diversity Analysis: Facilitates genetic diversity analyses by integrating publicly available genomic datasets with new data from global small ruminant populations.
• Livestock Adaptation Research: Supports research on adaptation of underutilized sheep and goat breeds to challenging environments, contributing to livestock sustainability.

Methodology:

SMARTER-database uses a collection of tools and scripts to standardize genomic data and metadata, mainly from SNP chip arrays, with a focus on reproducibility.