SnpTracker

SnpTracker maps and updates reference single nucleotide polymorphism (rs) IDs to their current genomic coordinates for human genetics and genomics research.

Key Features:

• Unified Tracking: Tracks rsIDs and their corresponding genomic coordinates for large sets of sequence variants simultaneously.
• Version Management: Extracts and assigns the latest rsID versions and their updated genomic coordinates from input rsIDs.
• Accuracy and Capacity: Surpasses existing utilities in accuracy and capacity for tracking and unifying rsIDs and genomic coordinates.

Scientific Applications:

• Post-GWAS Data Integration: Supports genetic data exchange and integration in the post-genome-wide association study (GWAS) era by providing accurate rsID and coordinate mappings.
• Data Consistency: Ensures identifier consistency across datasets by unifying variant rsIDs.
• Research Efficiency: Improves data management and integration efficiency for large-scale human genetics and genomics analyses.

Methodology:

Validated using proof-of-principle examples demonstrating accurate tracking and unification of rsIDs and genomic coordinates.