solGS
solGS predicts genomic estimated breeding values (GEBVs) from high-throughput genome-wide marker data to support genomic selection for quantitative traits in breeding programs.
Key Features:
- Genomic Estimated Breeding Values (GEBVs): Implements prediction of GEBVs using genomic marker data.
- RR-BLUP Modeling: Applies Ridge-Regression Best Linear Unbiased Predictor (RR-BLUP) for genomic prediction.
- High-throughput Genome-wide Markers: Operates on high-density genome-wide marker datasets for selection analyses.
- Data Management: Uses the Chado Natural Diversity database schema for storage and management of genomic and diversity data.
- Statistical Analyses: Estimates phenotypic correlation and heritability and computes selection indices.
- Data Visualization and Export: Generates graphical visualizations of analysis outputs and provides exports in text format.
- Adaptability: Employs a modular design to accommodate diverse datasets and breeding program requirements.
Scientific Applications:
- Genomic selection in breeding programs: Enables selection based on predicted GEBVs to improve quantitative trait outcomes and genetic gain.
- Implementation in cassava research: Applied within the NEXTGEN Cassava breeding database for cassava breeding and research.
Methodology:
Applies Ridge-Regression Best Linear Unbiased Predictor (RR-BLUP) to genome-wide marker data to predict GEBVs; estimates phenotypic correlation and heritability; calculates selection indices; stores data using the Chado Natural Diversity schema; and produces graphical outputs with text-format export.
Topics
Details
- Tool Type:
- web application
- Operating Systems:
- Linux, Windows, Mac
- Added:
- 5/21/2018
- Last Updated:
- 12/10/2018
Operations
Publications
Tecle IY, Edwards JD, Menda N, Egesi C, Rabbi IY, Kulakow P, Kawuki R, Jannink J, Mueller LA. solGS: a web-based tool for genomic selection. BMC Bioinformatics. 2014;15(1). doi:10.1186/s12859-014-0398-7. PMID:25495537. PMCID:PMC4269960.