SomeNA

SomeNA predicts protein–polynucleotide binding sites from protein sequences to identify residues involved in protein–polynucleotide interactions.

Key Features:

• Binding site prediction: Predicts protein–polynucleotide binding sites from protein sequences.
• Integration: Implemented as the component for protein–polynucleotide binding prediction within PredictProtein's functional prediction suite alongside ConSurf, metastudent, LocTree3, and ISIS2.

Scientific Applications:

• Functional annotation: Identification of residues implicated in protein–polynucleotide interactions to support annotation of protein function.
• Interaction mapping: Support for studies of protein–polynucleotide recognition and experimental design for mapping binding sites.

Methodology:

Computational prediction of protein–polynucleotide binding sites as implemented by the SomeNA predictor within the PredictProtein framework.