SpaceSequest

SpaceSequest conducts end-to-end analysis of spatial transcriptomics data from multiple platforms, enabling extraction of biological insights through standardized processing, platform-specific analyses, and automated cell type annotation.

Key Features:

• Multi-platform Support: SpaceSequest supports 10x Genomics Visium, Visium HD, Xenium, GeoMx, and CosMx spatial transcriptomics technologies.
• Standardized Quality Control and Data Processing: SpaceSequest performs standardized quality control and general data processing for spatial transcriptomics data.
• Platform-specific Analyses: SpaceSequest conducts key analyses customized for each individual spatial transcriptomics platform.
• Automated Cell Type Annotation and Deconvolution: SpaceSequest performs automated cell type annotation and deconvolution.
• Figure and Result Generation: SpaceSequest generates high-quality figures and analysis results.
• Visualization Integration: SpaceSequest integrates with cellxgene VIP and Quickomics for interactive visualization.

Scientific Applications:

• Spatial Transcriptomics Data Analysis: SpaceSequest enables comprehensive analysis of gene expression patterns in relation to tissue architecture across multiple spatial transcriptomics platforms.
• Biological Insight Extraction: SpaceSequest facilitates extraction of crucial biological insights from diverse spatial transcriptomics technologies through tailored computational methodologies.
• Cell Type Identification in Spatial Context: SpaceSequest enables automated identification and deconvolution of cell types within their native tissue spatial context.

Methodology:

SpaceSequest utilizes cutting-edge computational methodologies tailored for spatial transcriptomics analysis.